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LTL C12 BIO Test Series
LTL C12 Bio TEST 2 MOLECULAR BASIS OF INHERITANCE
Greetings from LEARN TO LEAD ACADEMY !!!
The number of attempts remaining is 2
Greetings from LEARN TO LEAD ACADEMY !!! All the best !!!
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2. In DNA strand, the nucleotides are linked together by
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3. Watson and Crick (1953) proposed DNA double helix model and won the Nobel Prize; their model of DNA was based on
(i) X-ray diffraction studies of DNA done by Wilkins and Franklin
(ii) Chargaff's base equivalence rule
(iii) Griffith's transformation experiment
(iv) Meselson and Stahl's experiment.
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4. If the sequence of bases in one strand of DNA is ATGCATGCA, what would be the sequence of bases on complementary strand?
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5. DNA replication takes place at _____________ phase of the cell cycle.
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6. The given flow chart shows central dogma reverse.
Enzymes used in processes A, B and C are respectively
A B C
(a) DNA dependent RNA dependent DNA dependent
DNA polymerase DNA polymerase RNA polymerase
(b) DNA dependent DNA dependent RNA dependent
DNA polymerase RNA polymerase RNA polymerase
(c) DNA dependent DNA dependent RNA dependent
RNA polymerase DNA polymerase DNA polymerase
(d) RNA dependent DNA dependent RNA dependent
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7. The enzyme DNA dependent RNA polymerase catalyses the polymerisation reaction in --------direction.
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8. During transcription, the site of DNA molecule at which RNA polymerase binds is called
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9. Polycistronic messenger RNA (mRNA) usually occurs in
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10. In transcription in eukaryotes, heterogenous nuclear RNA (hnRNA) is transcribed by
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11. Select the correct statements regarding the process of transcription in eukaryotes.
(i) The strand of dsDNA which takes part in transcription process is called as coding strand.
(ii) The enzyme RNA polymerase can catalyse polymerisation only in one direction i.e., 5' → 3'.
(iii) An unusual nucleotide methyl guanosine triphosphate is added to the 5' end of hnRNA during capping.
(iv) During tailing process, adenylate residues (200 -300) are added at 3' end in a template independent manner.
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12. Match column I with column II and select the correct option from the given code
Column I Column II
A. Sigma factor (i) 5'-3'
B. Capping (ii) Initiation
C. Tailing (iii) Termination
D. Coding strand (iv) 5'end
(v) 3' end
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13. The fully processed hnRNA is called as (i) and is transported out of the (ii) into the (iii) for translation.
(i) (ii) (iii)
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14. The three codons which result in the termination of polypeptide chain synthesis are
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15. Some amino acids are coded by more than one codon, hence the genetic code is
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16. The mutations that involve addition, deletion or substitution of a single base pair in a gene are referred to as
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17. Select the incorrectly matched pair.
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18. Amino acid acceptor end of tRNA lies at
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19. In a mRNA molecule, untranslated regions (UTRs) are present at
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20. Regulation of gene expression occurs at the level of
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21. Match column I with column II and select the correct option from the given codes.
A. Operator site (i) Binding site for RNA polymerase
B. Promoter site (ii) Binding site for repressor molecule
C. Regulator gene (iii) Codes for protein / enzyme
D. Structural gene (iv) Codes for repressor molecule
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22. Which of the following cannot act as inducer?
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23. Match column I with column II and select the correct option from the given codes.
A. Griffith (i) Lac operon
B. Hershey and Chase (ii) Semi-conservative DNA replication
C. Meselson and Stahl (iii) Transduction
D. Jacob and Monod (iv) Transformation
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24. Human genome consists of approximately
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25. Which of the following statements regarding 'human genome' is incorrect?
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26. Match column I with column II and select the correct option from the given codes.
Column I (Scientists) Column II (Discoveries)
A. Alec Jeffreys (i) Lac operon
B. F. Sanger (ii) Annotated DNA sequences
C. Jacob and Monod (iii) DNA fingerprinting
D. Avery, MacLeod and McCarty (iv) Transforming principle
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27. Both deoxyribose and ribose belong to a class of sugars called
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28. The net electric charge on DNA and histones is
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29. One of the following is true with respect to AUG
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30. The human chromosome with the highest and least number of genes in them are respectively
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31. Which was the last human chromosome to be completely sequenced ?
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32. The amino acid attaches to the tRNA at its
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33. To initiate translation, the mRNA first binds to
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34. In E. coli, the lac operon gets switched on when
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Directions: In the following questions, a statement of assertion is followed by a statement of reason. Mark the correct choice as;
35.Assertion: In Griffith's experiment, a mixture of heat- killed virulent bacteria R and live non-virulent bacteria S, lead to the death of mice.
Reason: 'Transforming principle' got transferred from heat-killed S strain to R strain and made it virulent.
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36. Directions: In the following questions, a statement of assertion is followed by a statement of reason. Mark the correct choice as ;
Assertion: Synthesis of daughter or new strand occurs continuously along the parent 3' → 5' strand.
Reason: DNA polymerase can polymerise nucleotides in 3' →5' direction on 5'→ 3' strand.
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37 .Directions: In the following questions, a statement of assertion is followed by a statement of reason. Mark the correct choice as:
Assertion : Lac operon is a repressible operon.
Reason: Regulation of lac operon by repressor is referred to as negative regulation.
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38. Directions: In the following questions, a statement of assertion is followed by a statement of reason. Mark the correct choice as:
Assertion: Eukaryotic mRNA requires post-transcription processing for formation of functional mRNA.
Reason: Eukaryotic transcripts possess extra non-functional segments called introns.
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39. Purines found both in DNA and RNA are
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40. Which is the "only enzyme" that has "capability" to catalyse initiation, elongation and termination in the process of transcription in prokaryotes?
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41. The experimental proof for semi-conservative replication of DNA was first shown in a
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42. If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6.6 x 10^9 bp. then the length of the DNA is approximately
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43. Match the following RNA polymerase with their transcribed products.
(1) RNA polymerase I (i) tRNA
(2) RNA polymerase II (ii) rRNA
(3) RNA polymerase III (iii) hnRNA
Select the correct option from the following.
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44. Which of the following types of RNA act as adapter molecule?
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45. The final proof for DNA as the genetic material came from the experiments of
Your score is
The average score is 17%
